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Recipes / John Wayne Casserole

John Wayne Casserole

August 25, 2025

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Introduction

The John Wayne Casserole is a rich, layered dish that combines a biscuit base with seasoned ground beef, peppers, onions, tomatoes, and a creamy cheese topping. Despite its cowboy name, this recipe became popular in community cookbooks and potlucks across the U.S., offering a filling and flavorful meal that’s sure to please. It’s one of those casseroles that’s simple to make yet bold enough to stand out at the dinner table.

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Ingredients

For the Base:

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  • 1 (16 oz) can refrigerated biscuit dough

For the Beef Layer:

  • 1 ½ pounds ground beef
  • 1 medium onion, chopped
  • 1 green bell pepper, chopped
  • 1 packet taco seasoning mix
  • ½ cup water

For the Tomato Layer:

  • 1 (10 oz) can diced tomatoes with green chilies (like Rotel), drained

For the Creamy Cheese Layer:

  • 1 cup sour cream
  • 1 cup mayonnaise
  • 8 oz shredded cheddar cheese
  • 8 oz shredded Monterey Jack cheese

Instructions

  1. Prepare the Base
    • Preheat oven to 350°F (175°C).
    • Grease a 9×13-inch baking dish.
    • Press biscuit dough evenly into the bottom to form a crust. Bake for 10 minutes, then remove.
  2. Cook the Beef Mixture
    • In a large skillet, cook ground beef, onion, and bell pepper over medium heat until beef is browned and vegetables are tender.
    • Drain excess fat. Stir in taco seasoning and water. Simmer for 5 minutes.
  3. Assemble the Layers
    • Spread the beef mixture evenly over the baked biscuit crust.
    • Sprinkle with drained tomatoes.
    • In a bowl, mix sour cream, mayonnaise, and half the cheeses. Spread this creamy mixture over the tomatoes.
    • Top with remaining cheese.
  4. Bake
    • Bake uncovered for 30–35 minutes, until the top is bubbly and golden brown.
  5. Serve
    • Let cool slightly before cutting into squares. Serve warm.

Storage & Reheating

  • Fridge: Store covered for up to 3 days.
  • Reheat: Bake at 350°F for 15–20 minutes or heat individual portions in the microwave.
  • Freezer: Wrap tightly and freeze before baking. Thaw overnight in the fridge, then bake as directed.
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I'm Emma, a food blogger passionate about creating flavorful and balanced recipes. I love sharing easy, wholesome meals made with fresh ingredients.
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